Special Pathogens Research Network, Limited

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Director General, Agwu, Ezera, PhD, FSAFRI

Dr Agwu Ezera is the Director General of Special Pathogens Research Network Limited. He is also the presiding editor of the special pathogen journals. He comes to Spparrenet Limited with the following competencies

 

a. Academic leadership: Talented in the provision of strategic leadership, handling, planning, organizing and directing the day to day running and operations of any academic/research institutions, including being responsible for oversight, review, evaluation and development of academic programs in an academic and research setting

Also skilled in development, implementation, monitoring and evaluation of policies and strategic development plans for both old and new programs in academic and research institutions with the ultimate goal of getting maximum result with minimum resources.

I am a gifted team player, initiator of researchable ideas and skilled in ensuring originality, continuity, flow and logical conclusion of publishable manuscripts.

b. Medical Education: Highly skilled in Health Sciences Education, Educational principles, Research scholarship, Leadership and specifically unique in Lecturing and Mentoring of Medical Microbiology, Parasitology and Immunology to both undergraduate and post-graduate students.

c. Molecular Approaches to Clinical Microbiology skills include: understanding microbial diversity at the species level: (16sRNA) and diversity at the subspecies level: (MLST); indexing diversity of genetically monomorphic bacteria: (VNTR and SNPS), identifying the diversity in the laboratory: (Real-time PCR), cataloguing and understanding diversity: (Bioinformatics approaches).

d. Molecular Biology and PCR: Genomic Cloning and DNA Sequencing, Genome Analysis, Gene Expression Analysis, cDNA Cloning and PCR Library Analysis, DNA Fingerprint Analysis and RNA Interference.

c. Protein profiling: 2-D gel electrophoresis, multidimensional liquid chromatography and affinity purification of protein complexes; MALDI and ESI high-sensitivity mass spectrometry including peptide mass mapping and tandem mass spectrometry, quantification, and phosphor-proteomics.

e. Functional proteomics: recombination cloning, high-throughput protein isolation, protein microarrays, use of  robots to execute high-throughput methods including expression, purification and characterization of proteins and also use of several bio-informatics tools in data analysis.

 

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Deetailed  Resume  of Dr AGWU Ezera

 

1.   Full Name: 

 

Agwu Ezera

 

2.   Post applied for:       

 

Professor of Medical Microbiology

 

3.   Present Position (since six years ago):  

 

Senior Lecturer of Medical Microbiology.

 

4.   Date of last promotion (six years ago):       

 

January 1, 2011

 

5.   Former administrative post held:

 

Dean of Faculty, Head of Department, and Chairman of various high profile University academic committees

 

6.   Date and place of birth  

 

January 7, 1973 at Amaekpu Ohafia LGA, Abia        State, Nigeria

 

7.   PERSONAL DATA

*Gender…………………………Male

            *Place & Date of birth………..Nigeria & 7th January, 1973.

            *Nationality ………………….Nigerian.

*Country of residence………..Uganda

           *Marital Status………………..Married

*Wife…………………………Barrister (Mrs) Queen Ezera Agwu

            *Number of Children………….Four

            *Names/Ages of children: … a. Joseph Ezera Agwu/9years

                                                            b. Ogbeyalu Ezera Agwu/6years

c. Oyidiya Ezera Agwu/4years

d. Awa Ezera Agwu/2 year

 

8.   Permanent Home Address

 

Through Mr Agwu Ngwoke, No 5 Ohafia Street, Umuahia, Abia State,   Nigeria

 

9.   Current postal address including mobile telephone number

 

Office of the Chair, Disease Intervention and management Failure (DIMAF), Research Group, Department of Medical Microbiology and Immunology, Faculty of Basic Medical Sciences, Kampala International University, Western Campus, Ishaka, Box 71, Bushenyi, Uganda. E-mail: drezera@spparenet.us and agwuezera@yahoo.com Tel: +256782101486 and +256703129679

 

10.   MY UNIQUE SELLING PROPOSITION

I am an experienced Medical Microbiologist, with strong diagnostic, molecular biology and medical education background, talented in the initiation of new programs and strengthening of existing ones, provision of strategic leadership in research, academics and administrative protocols ultimately making professionals out of generally disadvantaged population

 

11.  STATEMENT OF MY TEACHING PHILOSOPHY

Good teaching is the ability to capture students’ attention and interest, clarify difficult topics, guide the student through complex areas and put knowledge into context so that its relevance becomes clear. It is also the ability to inspire curiosity in any subject or topic with the ultimate goal of providing effective and practical ways to satisfy their curiosity.

I desire to achieve this by the following approaches:

 

a.       I encourage students to think in a rational way or learn to think about the trend or logic behind every argument or fact rather than routine memorization of facts. I encourage them to always ask the “how” and “why” questions in every topic so that when the answer is provided it will induce a sense of amazement in them which will lead to more questions.

b.      I teach them by example and not just by dictating set of rules. Thus I teach them my own principles of life which have worked for me such as: small group work or reading, dedication and love for courses even if they do not like the lecturers, contentment with what they have to avoid distraction, personal sacrifice of time and resources to get knowledge, patients because there is time for everything, emotional stability especially over issues they cannot change, courage and optimism about success because short cut does not pay and others…

c.       I help my students to learn by providing the right atmosphere and necessary information needed to learn in a problem based approach so that they do not see me as an expert who just delivers information to students. Using a feedback mechanism, I am able to know their different preferred learning styles and rates, what they have already acquired and what they need to know in the future and how best I can help them learn in small groups.

d.      I emphasize the need for students to see me at a designated time for students in my office or library and during working hours for any questions about the topics we have discussed in class or topics in Microbiology which is of interest to them. This is because I know personal contact to students have significant impact to slow curious learners for which class room teaching may not be enough.

 

Their fascination lies on my ability to demystify Microbiology by linking the microbial world with human activities in a country or state. Thus each student leaving the class knows that there is another population of unseen living things like humans which inhabit the world, struggling for existence, fighting each other, and with human race, with names, tribes, races, families like in the human world. They understand how microorganisms study: science likes us to provide resistance to our antibiotics; humanities and arts to understand how to spread, Anatomy, Physiology and biochemistry to be able establish infection in healthy host and so on. From my feedback, while 10% comes to my class to laugh, 70% comes to learn and smile, and another 20% comes to smile and later learn by asking me questions and studying in a small group.

The above approaches probably increased the student’s desire for my opinion in different aspect of Microbiology. Consequently I have already produced some books based on my 15 years University class room teaching, community oriented services and research experience. The books are: (1). “Practical manual in Medical Microbiology and Parasitology”, (2). “Human Microbial infections”, (3). “The Foundation of Medical Microbiology and Parasitology” and (4). Research Methods in Biomedical Sciences. 

 

12. SKILLS 

a. Medical Education: Health Sciences Education, Educational principles, Research scholarship and leadership.

b. Molecular Biology, PCR, Protein profiling, Functional proteomics, understanding microbial diversity at the species and subspecies level: (16sRNA and MLST) indexing diversity of genetically monomorphic bacteria: (VNTR and SNPS), identifying the diversity in the laboratory: (Real-time PCR), cataloguing and understanding diversity: (Bioinformatics approaches).

 

13. Institutions attended with dates

 

S/N

Educational institutions attended

dates

        i.            1

Ambrose Alli University, Edo State, Nigeria

2004-2010

      ii.            2

Ambrose Alli University, Edo State, Nigeria

2001-2003

    iii.            3

University of Calabar, Cross River state, Nigeria

1994-1998

    iv.            4

Federal School of Arts and Sciences, V/ Island Lagos

1992-1993

      v.            5

Methodist College, Uzuakoli, Abia State, Nigeria

1988-1991

    vi.            6

Ohafia Girls Secondary School, Abia State, Nigeria

1985-1987

  vii.            7

Ntalakwu Central School, Bende, Abia State

1978-1985

 

14. Academic qualifications obtained with dates  

 

S/N

Academic qualifications obtained

Dates

a.        

[Ph.D], Doctor of Philosophy degree in Medical Microbiology & Immunology

April 14, 2010

b.       

[M.MLS]. Masters in Medical Laboratory Sciences, (Specialization in Medical Microbiology & Parasitology)

December 23, 2003

c.        

B.Sc. (Hons)  Bachelor of Sciences in Medical Laboratory Sciences (Specialized in Medical Microbiology & Parasitology)

October 16, 1998

d.       

[SSCE], Senior School Certificate

June 1992

e.        

[FSLC], First School Living Cert

June 1985

 

15.  Professional qualification obtained with dates 

S/N

Professional qualification obtained

Dates

        i.             

[A.IMLS]. Associate, Institute of Medical Laboratory Sciences 

July 2001

      ii.             

Post-graduate Certificate: Molecular Microbial diversity

2009

    iii.             

Post-graduate Certificate in Functional Proteomics & Protein profiling

November 2007

    iv.             

Post-graduate Certificate in Molecular Biology and PCR

July, 2007

      v.             

Post-graduate Diploma in Medical Education

2008-2010

 

 

16. Work experience with dates

 

a. ADMINISTRATIVE EXPERIENCE:

1.      Chair, DIMAF, KIU-WC. November 27, 2014 till date

Disease Intervention and management failure (DIMAF) Research division, Department of Microbiology and Immunology, Faculty of Basic Medical Sciences, Kampala International University, Western Campus, Ishaka, Bushenyi, Uganda.

 

·         Provision of strategic leadership to DIMAF and ensuring that old and new members conform to the tenets of the research division while fulfilling their official tasks as lecturers in KIU

·         Championing innovative ways of reducing incidences of treatment failure and failed intervention by use of cutting edge technologies to answer hard questions not possible by routine or conventional means

·         Establishing collaborations with local, national and international organizations  

·         Organize and chair meetings and workshops aimed at achieving the objectives of DIMAF

·         Lead DIMAF in the area of capacity building in research and academics   

·         Lead DIMAF to source for, develop research concepts and proposals for competitive grants.

·         Present research papers to audience at conferences and meetings portraying the progress of DIMAF in East African sub-region    

·         Lead DIMAF in establishing and strengthening a journal club and to publish research papers to highly visit and high impact factor journals.

·         Lead DIMAF to disseminate the research findings to affected communities and to implement result oriented interventions

·         Lead DIMAF to develop and stay focused on the strategic development plan for both the research group and the Department of Microbiology at large.                   

 

2.      DEAN                                            December 3, 2009 till July 21st 2015

School of Allied Health Sciences, Kampala International University, Western Campus, Ishaka, Bushenyi, Uganda

a)      Provides strategic leadership to the school of Allied Health Sciences, KIU-WC

b)      Handling, planning, organizing and directing the day to day running and operations of the school, including being responsible for oversight, review, evaluation and development of academic programs

c)      Overseeing and coordinating University examinations in the school and also ensuring continuous improvement of the curriculum of all program offered in the school with a focus on content, format and method

d)     Convening and chairing school board meetings coordinate

e)       Meeting regularly with the school heads of departments to discuss training requirements and effectively administering evaluation tools for academic staff performance to ensure quality of programs

f)       Monitoring and ensuring adherence to all school time tables

g)      Developing and implementing strategic planning  specific to programs within the school including staffing and examination

ii. HEAD OF DEPARTMENT August 27, 2007-December 2, 2009

Department of Medical Microbiology & Parasitology, both in the Faculty of Biomedical Sciences and at the Teaching Hospital of Kampala International University, Western Campus, Ishaka, Bushenyi, Uganda

 

a)      Provided Leadership and Coordination of Microbiology Research unit of the University and routine Diagnostic activities in our Teaching Hospital;

b)      Coordinated the teaching and evaluation of Basic and Applied Medical Microbiology & Parasitology by the Department;

c)      Allocated lectures topics to Lecturers; maintain discipline in the department;

d)     Recommended to the DVC Administration and Executive Director of the Teaching Hospital on issues related to staff development and recruitment.

e)      Headed the committee which drafted and monitors the performance of Standard Operational Procedures guiding the usage of equipment in the department;

f)       Identified and recommended external examiners for all Microbiology exams, coordinates departmental seminars

g)      Headed the committee which reviewed the Microbiology aspect of integrated PBL curriculum for MBBS program and drafted the curriculum for undergraduate and post-graduate Microbiology degree programs

h)      Ensuring that Microbiology services are provided twenty four hours through designing of effective monthly call-duty roosters

i)        Supervised the purchase & maintains Microbiology equipments/consumables 

j)        Still responsible for coordination of departmental seminars and organization of activities of Infection control committee of our Teaching Hospital and University

 

b. ACADEMIC EXPERIENCE:

i         SENIOR LECTURE- MEDICAL MICROBIOLOGY (Six years): From January 1, 2011 till DATE. KIU-Western Campus

ii.         LECTURER- MEDICAL MICROBIOLOGY: 01/10/2005 till 31/12/2010

Department of Medical Microbiology, School of Health Sciences, Kampala International University, Western Campus, Ishaka, Uganda

 

a)      Lecturer of Medical Microbiology and Parasitology, Microbial genetics, Pharmaceutical Microbiology, Research methods, Medical Microbiology Ethics and Medico legal Issues, Advanced Microbiology, Systematic Bacteriology and Mycology, Public Health Microbiology, Automation in Biomedical Instrumentation and basic Immunology to students of Microbiology, Medicine and Surgery, Nursing Sciences, Diploma in Clinical Medicine, Medical Laboratory Sciences, and Pharmacy undergraduate and post-graduate students.

b)      Chair, Pharmaceutical Microbiology lectures and programs at the School of Pharmacy, Kampala International University and subjects I teach includes: Pharmaceutical Microbiology and Assessment of the Quality of Biological Products.

c)      Chair: Disease Intervention and Management Failure (DIMAF) Research Group, Department of Medical Microbiology and Immunology, KIU western Campus Uganda.

d)     Chair, Curriculum development monitoring & evaluation committee (CDMEC) in Microbiology and Immunology Department

e)      Supervises undergraduate and post-graduate students’ research projects in Microbiology and Infectious disease

f)       Chairman of Departmental Tropical Disease Research Committee

g)      Graduate school representative for departmental post-graduate programs

h)      Member Kampala International University Research and Ethics Committee

 

iii. LECTURER   & MEDICAL LABORATORY SCIENTIST          

2000 till 29/10/2005.

 

Department of Medical Microbiology, Faculty of Clinical Sciences, College of Medicine Ambrose Alli University, Box 14, Ekpoma Edo State Nigeria

a)      Lectured General Microbiology and Bacterial Physiology in the Department of Medical laboratory Sciences, Faculty of Basic Medical Sciences, College of Medicine, Ambrose Alli University, Ekpoma Nigeria.  

b)      Assisted in drawing up of proposal for a standard Medical Microbiology Laboratory, suitable for teaching clinical students as demanded by management upon assumption of duty in the year 2000.

c)      Charged with the responsibility of Teaching and Assessing Medical Students, Practical Medical Microbiology and Parasitology.

 

iv. Youth Corps Member (NYSC):            1999-2000

      General Hospital Kamba, Kebbi State, Nigeria

·         Headed the laboratory unit of the hospital and assisted in the training of students on industrial attachment and other members of staff mostly laboratory assistants and other non-professionals employed to work in their laboratory.

 

v. Intern Scientist:                                    1998-1999

Federal Medical Center, Umuahia, Abia State, Nigeria

  • Did joint Departmental call-duties and Routine laboratory investigations in the Departments of: Medical Microbiology and Parasitology, Hematology & Blood Transfusion, Chemical Pathology, and Histopathology

 

17. Conference/courses attended (state title of papers presented if any)

 

a.      Molecular Approaches to Clinical Microbiology in Africa- May 24-30, 2009, a Wellcome-Trust advanced course issued by Wellcome Trust Genome Campus, Hinxton Cambridge, CB10 1SA, UK

 

  1. The 19th European Congress of Clinical Microbiology and Infectious Disease (ECCMID) meeting held in Helsinki from 16 - 19 May 2009.

 

  1. Annual Proteomics training course organized by Cold Spring Harbor Laboratory held from November 6 to 19, 2007, New York, USA.

 

  1. The 46th Annual Meeting of Inter-science Conference on Antimicrobial Agents and Chemotherapy (ICAAC) and Infectious disease society of America (IDSA) held in Washington DC, USA, 2008. Control Number: 3253.

 

  1. Second Session of New England Biolabs Molecular Biology Summer Workshop at Northampton, MA, USA between July 15-28 2007.

 

  1. Second Biomedical Engineering Conference (UMUAHIA 2001) held between 25th and 27th October 2001 at Empire Hotels, Umuahia Abia State. Nigeria.

 

  1. Third Biomedical Engineering Conference (LAGOS 2002), held between 24th -27th October 2002, at Lagos University Teaching Hospital Idiaraba, Nigeria.

 

  1. 8. Thirty ninth Annual Scientific Conference and workshop (OGUN 2003), of Association of Medical Laboratory Scientist of Nigeria, held between 19th -23rd of August 2003. at the Gateway Hotel, Abeokuta, Ogun State, Nigeria.

 

  1. Twenty eight Microbiology Society of Nigeria Annual Conference and General Meeting (EKPOMA 2004), held between 17th & 20th November 2004 at the Ultra-Modern Lecture Theater, Ambrose Alli University, Ekpoma Edo State Nigeria.

 

18. Title of Papers presented at Conferences

 

a.        Agwu E. Review of Molecular techniques used to detect fungal opportunistic infections associated with HIV/AIDS, at the 4th National Scientific Conference, Mycology Society of Nigeria, 19-22 September 2010. (Invited Key-Note Speaker)

b.      Agwu E. Antimalaria drug resistance at the First National Scientific conference on Rational Drug use in developing countries, by Pharmacy students Association KIU, held at KIU-WC, between 26-27th, February 2010.

c.       Agwu E., Masters in Medical Microbiology is urgently needed by Uganda stakeholders, a poster presentation at the third annual scientific conference of South African Association of Health Educationist (SAAHE) held at the University of Witwatersrand, Johannesburg, South Africa between 22nd and 24th July 2010.

d.      Agwu E. Long term challenge of routine co-trimoxazole prophylaxis among a population of Ugandan HIV infected and AIDS patients; oral presentation at the 1st Family Medicine National Scientific conference, held at the Grand Imperial Hotel, Kampala Uganda between 26th and 27th November, 2009.

e.       Agwu E, L. Wambua, L. Titus. Sentinel survey of typhoid prevalence among febrile patients attending clinics in Bushenyi district of Uganda; presented as a poster at the 19th European Congress of Clinical Microbiology and Infectious Disease (ECCMID) meeting held in Helsinki from 16 - 19 May 2009.

f.       Agwu E, G. Tananyen Randomized health-point surveillance of human gastro-intestinal parasites among patients attending a teaching hospital in Ishaka, Uganda; presented as a poster at the 19th ECCMID meeting, Helsinki, 2009.

g.      Agwu E, J. Ihongbe, N. Inyang, Prevalence of quinolone susceptible Pseudom. aeruginosa and Staph. aureus in delayed-healing diabetic foot-ulcers in Ekpoma, Nigeria; as a poster at the 19th ECCMID meeting, Helsinki, 2009.

h.       Inyang NJ, Enweani IB, Agwu E, Esumeh FI, Obiazi HAK, and Efedeyi RA. Molecular Typing of Yeasts from Symptomatic, Asymptomatic Women and Asymptomatic Pregnant Women in Ekpoma, Nigeria presented as poster at the 46th Annual Meeting of ICAAC/IDSA. Washington DC, 2008. C. Number: 3253.

i.        Agwu E., Isibor JO., Okogun G. R. A., Ekpoke J., Onyebuagu P. C., and Nwaopara A.O. Evaluation of the immunogenicity of locally prepared somatic antigens of Salmonella typhi. Third Biomedical Engineering Conf. Lagos 2002

j.        Nwaopara AO., Agwu E., Onyebuagu, P.C., Umeni A.O.  Mouth moistening of the finger during manual counting of naira notes as a habit among naira-notes users in Nigeria. Second Biomedical Engineering Conference: Umuahia Nigeria 2001

 

 

19.  Professional accomplishments with Research interest and activities

 

             A. Medical education activities (Curriculum development)

As a trained Medical Educationist (FAIMER fellow), I am competent in: Health Sciences Education, Educational principles, Research scholarship and leadership with particular interest in curriculum development and youth leadership.

Ten University curricula developed and implemented under my leadership include:

 

  1. Bachelor of Medical Laboratory Sciences in: (1. Haematology and Blood Transfusion, 2. Chemical Pathology, 3. Microbiology and Parasitology, 4. Histopathology)(BMLS)
  2. Diploma in Medical Laboratory Technology (DMLT)
  3. Bachelor of Sciences in Microbiology (B. Sc)
  4. Master of Sciences in Microbiology (M.Sc)
  5. Doctor of Philosophy in Microbiology (Ph.D)
  6. Bachelor of Clinical Medicine and community Health (BCM&CH)
  7. Bachelor of Public Health in (Health System Management, Health Education/Promotion and Nutrition) [BPH]
  8. Master of Public Health in (1. Biostatistics, 2. Environmental Health, 3. Epidemiology and Disease Control, 4. Nursing, 5. Bioethics & Human Rights, 6. Health Policy and Law, 7. Disaster Management, 8. Maternal & Child Health, 9. Nutrition and food security, 10. Health system management, 11. Health education and counselling, 12. Health intervention and Promotion). [MPH]
  9. Microbiology aspect of the curricula for Medicine and surgery program, Pharmacy, Nursing Sciences, Biomedical sciences courses
  10. Master of Medicine in Microbiology [M.Med-Micro]

 

Competent in conducting needs assessment before curricula are developed and projects concepts and proposals are developed. Proof is a paper published after the needs assessment for one of the curricula I developed as listed above.

 

Agwu E. 2010. The need for a Master of Sciences degree program in Microbiology in Uganda. African Journal of Health Professions Education, 2 (1): 21-22. See the paper through the link below: http://www.ajhpe.org.za/index.php/ajhpe/article/view/54

 

B. Molecular Biology and Infectious disease training workshops          organized 

a. Annual molecular-biology and Bio-informatics training workshop for healthcare providers and postgraduate students since 2012.  Click the link to see more. http://www.spparenet.us/Mol%20Biol.html

 

  1. Annual Mycobacterium tuberculosis and Plasmodium species Microscopy training workshop for laboratory staff in resource limited settings since 2012. Click the link to see more. http://www.spparenet.us/Microscopy.html

 

  1. Annual Mycobacterium interspaced repetitive units variable numbers of tandem repeats [MIRU-VNTR] genotyping workshop since 2014. Click the link to see more.  http://www.spparenet.us/Workshop%202014.html

 

  1. Annual Free Medical Camp for rural and hard to rich country dwellers since 2014. Click the link to see more  http://www.spparenet.us/Med%20Camp.html 

 

  1. Annual HIV/AIDS and Microscopy training workshop for healthcare providers in developing countries since 2014. Click the link for more details http://www.spparenet.us/Microscopy%20-%202.html

 

c. Awards

  1. Institutional award: Current chairman Community Based Education, Research, Management and Services [COBERMS] sub-committee and former chairman, Medical Education sub-committee for 2 years  during the on-going NIH five years Medical Education Partnership Initiative [MEPI] Institutional Award to establish Medical Education equitable services for All Ugandans [MESAU].

 

  1. Name of award: Financial Assistance to attend a one week Course/Workshop on Molecular Approaches to clinical Microbiology in Africa @ College of Medicine University of Malawi, Blantyre, Malawi. Awarding Body: The Wellcome Trust, UK. Amount/Month/Year: Seven Hundred British Pounds (B£700)/2009.
  2. Name of award: Financial Assistance to attend a two weeks Course/Workshop on Proteomics @ Cold Spring Harbor Laboratory, New York State, USA. Awarding Body: Cold Spring Harbor Laboratory. Amount/Month/Year: Five thousand nine hundred and fifteen US dollars (US$5,915)/November/2007.
  3. Name of Award: Five weeks Travelling Fellowship. Awarding Body: Journal of Cell Science, the Company of Biologists Ltd. Cambridge, CB40DL, UK. Amount/Month/Year: Four thousand US, (US$4000)/May-June/2007.
  4. Name of award: Five weeks Development Traveling Fellowship. Awarding Body: The Company of Biologists Ltd (Development), Well-come Trust/Cancer Research UK Gurdon Institute, Cambridge, UK. Amount/Month/Year: Two thousand and five United States Dollars, (US$2005)/May-June/2007
  5. Name of award: Financial Assistance to attend two weeks Molecular Biology Summer Workshop, Smith College, Northampton MA, USA. Awarding Body: New England Biolabs, Northampton, MA, USA. Amount/Month/Year: Three thousand nine hundred US dollars (US$3,900)/July/2007
  6. Name of award: Five weeks Collaborative Research Assistance. Awarding Body: Division of Oral Bioscience, Dublin Dental School and Hospital, Trinity College, University of Dublin, Republic of Ireland. Approximate amount: Ten thousand Euros €10,000/May-June/2007
  7. The AIDS Support Organization (TASO) gave one thousand three hundred US dollars (US$1300) worth return ticket to and from Dublin for five weeks during the analysis of oral yeast isolates for this investigation
  8. Name of Award: Six months Research Assistance (2006). Awarding Body: Kampala International University, Western Campus, Uganda. Approximate Amount: Six million Uganda Shillings (US$ 3000).
  9. Best poster presenter during the 7th Annual Scientific conference MAK-CHS and 19th UNACOH annual scientific conference, Speke Resort Munyonyo Kampala, Uganda 2011.

 

D. Honors

a.       Appointed member to represent Microbiology & Parasitology, on the committee for procurement and maximum interdepartmental utilization of Laboratory Facilities, Faculty of clinical Sciences, College of Medicine, Ambrose Alli University, Box 14, Ekpoma, Edo State Nigeria. (2001-2005).

 

  1. Appointed Secretary of a 5-man committee for harmonization of research proposals from School of Health Sciences, Kamapala International University, Western Campus (2005 till date)

 

  1. Appointed member, Kampala International research and ethics committee. Kampala International University, Western Campus, 2006-till date.

 

  1. Appointed Chairman, infection control, Kampala International University Teaching Hospital (KIUTH) 2007 till date.

 

  1. Appointed: Elder, United Faith Chapel, Kampala International University, Western Campus, Uganda; Evangelism Leader, Scripture Union Nigeria, Ekpoma pilgrims group and President Christian Undergraduate Fellowship Ohafia, Abia state Nigeria

 

20.  Research interest

 

a. Public Health Microbiology: To outline the population genomics and transmission dynamics of microbial agents of tropical infections in: HIV/AIDS; Febrile Illness; diabetes and ulcerative soft tissue infections. Disease diagnosis, prevention and control remain a health challenge in developing county settings partly because of changing disease aetiology in different health conditions. Understanding the dynamics of changing disease aetiology will impact on our capacity to diagnose, prevent and control infections

 

b. Molecular Diagnosis: To identify, characterize and study the functions of genes that play critical roles in cell signaling, differentiation, and replication. By exploiting the powerful genetics of pyogenic cocci, yeast and emerging resistance in enterobacteria, I hope to elucidate the function of these proteins and ultimately use this knowledge to devise strategies for effective treatment of oral cancers and other human diseases

 

c. Molecular Epidemiology: To study: the changes in the oral microbiota and skin/soft tissues, and their contribution to the oral complications associated with diabetes and HIV disease; the host and/or environmental factors that will facilitate infection of human epithelial cells with bacteria pathogens and to study the complications associated with the prolonged use of medication in diabetes treatment and also prolonged use of Highly Active Anti-Retroviral Therapy in patients with HIV including etiology, host susceptibility, early detection and prevention. Examining the effects of HAART on the any human mucosal milieu is likely to elucidate the conditions that appear conducive or protective to the studied lesions. Moreover, understanding the potential interactions between oral mucosa and many environmental factors in the context of HIV infection will provide insight into their influence on the pathogenesis of the AIDS related oral and other soft tissue disorders.

 

d. Use of molecular approaches in the study of the population structure and transmission dynamics of selected vector borne tropical diseases with emphasis on malaria  

 

21.  Research activities

 

Post-graduate projects-(PHD) supervised

1.        Inyang: Molecular Characterization of yeast species among symptomatic and asymptomatic women attending Irrua Specialist Hospital, Edo State, Nigeria.

2.        Ezeonwumelu: “Evaluation of Biopharmaceutical values of Bidens pilosa, Ageratum conyzoides and Ocimum swave used in the management of oral lesions of HIV/AIDS patients in Uganda”

Post-graduate projects-(PHD) in-progress

1.        Dahiru: Microbiological evaluation of Nicin-colicin complex and its application in the control of Human, Animal and Plants diseases in Kano state Nigeria 

2.        Bashiru: Molecular Epidemiology of Acinetobacter species associated Hospital acquired infections in Kano state Nigeria. 

3.        Ordoki: Molecular Epidemiology of Salmonella Species and other Extended spectrum beta-lactamase-ESBL, producing bacteria in known diabetics with UTI in South Western Uganda.  

4.        Maniga: Epidemiology and genetic diversity of Malaria Parasites in Bushenyi District of Uganda.

5.        Emmanel Eileu. Microbial predictors of Uro-genital carcinoma in sexually active women in south western Uganda. 

 

Post-Graduate Projects-(Master’s Degree) Finished

1.        Muhamad: Genetic basis of resistance in Mycobacterium tuberculosis infections in Aminu Kano Teaching Hospital in Kano state Nigeria

2.        Gulemye: Microbiological contamination of locally prepared fresh fruit juice served at restaurants in Bushenyi district, Uganda

3.        Aiyegbusi: Appraisal of factors affecting utilization of delivery services in hospitals by pregnant women in Bushenyi district, Uganda

4.        Mugisha: Cross-border movement and its effect on the spread of HIV/AIDS in Kisoro district south-western Uganda.

5.        Makame: Influence of low latrine coverage on diarrhoeal disease distribution in northern ‘a’ district of Zanzibar, Tanzania

6.        Odoki: Molecular epidemiology of urinary tract infections in HIV/AIDS patients living in Gulu districts of Uganda

7.        Biodun: The Epidemiology of infectious diseases among the alcoholic in living in Bushenyi 
district of Uganda
8.        Baguma: Epidemiological study of nosocomial bacterial infections of the soft tissue in Kabale and Bushenyi 
districts of south-western Uganda.

9.        Umwanankundi : Health-point survey of malaria-helminthiasis co-infections among anaemic preschool and school-age children in Bugesera district, Rwanda

10.    Grace: Comparative  analogy  of  serological  and  microscopic detection  of  plasmodium  species  among  children  below 5  years    in  Kampala  international  university teaching  hospital  Bushenyi  district  Uganda.

11.    Amanyire: Pattern of stigmatization and discrimination among HIV positive clients attending TASO Mbarara clinic- Uganda

12.    Agensi: Factors affecting the Microbiological quality of Bikingi gravity water Kisoro district, Uganda

13.    Kyarimpa: Abuse of antimalarial drugs in treatment of febrile patients clinically diagnosed of malaria in Bushenyi District Uganda

14.    Baluku: Epidemiology and factors affecting the distribution of Cholera in Kasese District, Uganda.

 

Under-Graduate Projects- Finished

1.      Shabohurira: A survey of bacterial agents of pelvic inflammatory disease (PID) among women attending Kampala International University Teaching Hospital Bushenyi, Uganda

2.      Joseph: Prevalence of healthcare associated nosocomial Pneumonia disease in Bushenyi, district of Uganda

3.      Muddu: Prevalence of Salmonella Typhi and Intestinal Worms among Food Handlers in Masindi Municipal Council, Masindi District*

4.      Barinbuuza: Microbiological impact of traditional home deliveries on infant mortality in Bushenyi district of Uganda

5.      Wambua: Sentinel survey of typhoid prevalence among febrile patients attending clinics in Bushenyi district of Uganda

6.      Magithi: Sentinel survey of the prevalence of syphilis infection among patients clinics in Bushenyi district Uganda

7.      Joram: Pattern of malaria prevalence among febrile patients treated with chloroqine, fansider, and quinine in South Western Uganda.

  1. Gulemye: The burden of bacterial and parasitic agents of diarrhoea and resistance profile of bacteria from stool samples of hospital attendees in Bushenyi, Uganda
  2. Eribu: Widal Serological test remain a reliable diagnostic test for typhoid in resource poor settings like Uganda
  3. Mutambi: Pattern of stigmatization and discrimination among HIV positive patients attending clinics in Mbarara metropolis Uganda
  4. Byaruhanga: Microbiological analysis of wound infections among patients attending clinics in Bushenyi- Uganda
  5. Oming: The prevalence of Cryptosporidiosis in diarrheal patients attending clinics in Kampala International University Teaching Hospital, Bushenyi District Nigeria.
  6. Okello: Prevalence of Pulmonary tuberculosis and malaria among HIV infected and AIDS patients AIDS patients in Bushenyi
  7. Muganzi: Prevalence of Syphilis and hepatitis B surface antigen among HIV/AIDS patients in Bombo military hospital, Uganda
  8. Kinobere: Analysis of malaria prevalence and its associated co-infection among paediatric patients attending clinics in Bushenyi district of Uganda

16.  Omar: A survey of the puerperal sepsis in Masaka Regional Referral Hospital, Masaka, Uganda

17.  Shikaro: Assessment of pneumonia among pediatric patients attending Masaka regional referral hospital.

18.  Victoria: Prevalence of schistosomiasis among patients attending Bwera Referral hospital in Kasese district, Uganda.

 

 

22.  Publications with dates

 

1. Olufunke AV, Agwu E. Uptake of hospital based delivery services in Bushenyi District, Uganda. Special Pathogens Review Journal (SPRJ), 2016;1(1):40-50. See the paper through the link  http://www.spparenet.us/SPRJ/?page_id=234

 

Key message: In this paper the acceptance of hospital based delivery services in Bushenyi district, of Uganda. Was tested to assess its impact on distribution of associated diseases in the study region. Result may have policy implications.

 

2. Agwu E, Oming S, Moazzam ML. Prevalence of Cryptosporidiosis among diarrhea patients attending clinics in Bushenyi district of Uganda. Special Parasites pathogens Journal (SPPJ), 2015; (1)1: 14-19. See http://www.spparenet.us/SPPJ/?page_id=125

 

Key message: In this paper the Burden of Cryptosporidium species among Diarrhea was surveyed so as to highlight the pattern of parasite distribution among diarrhea patients in Bushenyi, Uganda.

 

3. Baluku M, Agwu E, Kasule A, Moazzam ML. The transmission dynamics of cholera epidemic in Kasese district, Uganda. Special pathogens Review Journal (SPRJ) 2015; 1(1):30-39.  See http://www.spparenet.us/SPRJ/?page_id=194  

 

Key message: In this paper the appraisal of factors influencing cholera distribution was conducted to determine why cholera remained endemic despite existing good interventions.  

 

4. Joram GO and Agwu E. Retrospective evaluation of malaria parasites distribution among febrile patients attending clinics in Bushenyi district, Uganda. Special Parasites Pathogens Journal (SPPJ) 2015; 1 (1): 7-12.  See http://www.spparenet.us/SPPJ/?page_id=101 

 

Key message: In this paper the distribution of Malaria parasite was retrospectively assessed to determine the burden of malaria parasites among febrile patients in Bushenyi Uganda.

 

5. Mugisha S and Agwu E: Cross-border movement of people and its effect on the Spread of HIV/AIDS in Kisoro district south western Uganda. Special viral pathogens Journal [SVPJ], 2015; 1 (1): 26-34. See  http://www.spparenet.us/SPPJ/?page_id=77   

  

Key message: In this paper the burden of HIV/AIDS disease distribution was blamed on the cross boarder movement in a strategic borderline town of Kisoro district in Uganda.

 

6. Agwu E, Tanayen G and Moazzam ML. Four-year health-point surveillance of Human Gastro-intestinal parasites among patients attending a clinic in Bushenyi, Uganda. Special Parasite Pathogens Journal (SPPJ) 2015; 1 (1):1-6   
See  http://www.spparenet.us/SBPJ/?page_id=212   

 

Key message: In this paper the intestinal parasites prevalence in a Bushenyi district were surveyed for use by healthcare providers in healthcare provision.

 

7. Kasule A and Agwu E. Health budget shortfalls and inefficient communication systems as setback to efficient management/control of infectious disease in Bushenyi district, Uganda. Special Pathogens Review Journal, (SPRJ) 2015; 1(1): 12-17. See paper via link below:

http://www.spparenet.us/SPRJ/?page_id=144  

 

Key message: In this paper, budget shortfalls impacts on management and control of infectious disease in Bushenyi, Uganda.

 

8. Kasule A and Agwu E. Review of health workers attrition and microbial disease endemicity in Bushenyi, Ntungamo and Rukungiri Districts of South Western Uganda. Special Pathogens Review Journal, (SPRJ) 2015; 1 (1): 1-11. See paper via link below:

http://www.spparenet.us/SPRJ/?page_id=124

 

Key message: In this paper, health workers refusal to stay and work in remote villages were surveyed with the ultimate goal of finding a solution for retention to provide services in the remote villages.

 

9. Inyang NJ, Enweani IB, Agwu E, Esumeh FI, Obiazi HAK, Eifediyi RA, Ikheloa J. Colonization and susceptibility profile of vaginal yeast isolates in Ekpoma, Edo state Nigeria. Special Fungal Pathogens Journal (SBPJ) 2015; Vol 1, No 1: p 0007-0013. See paper here http://www.spparenet.us/SFPJ/?page_id=26

 

Key message: In this paper pattern of virginal yeast colonization and susceptibility were surveyed with the ultimate goal of providing a database for future use in the management of genital yeast infection in this region.

 

10. Micheni L, Agwu E, Maniga J, Okech MA, Ponchang W, Distribution of medically important saprophytic Zygomycetes species in Bushenyi District, Uganda. Special Fungal Pathogens Journal (SBPJ) 2015; 1 (1): 1-7. See http://www.spparenet.us/SFPJ/?page_id=88

 

Key message: In this paper, Zygomycetes species in the soil around Bushenyi district were surveyed so as to be able to predict the possible source of future outbreak.

 

11. Ikheloa J, Inyang NJ, Adelekun A. Agwu E

Molecular analysis of methicillin resistance and beta-lactamase production by clinical isolates of Staphylococcus aureus in Ekpoma, Edo State Nigeria. Special Bacterial Pathogens Journal, (SBPJ) 2015; 1 (1):16-22. See http://www.spparenet.us/SBPJ/?page_id=212                                                                                                                                                                                       

Key message: In this paper methicillin resistance and beta-lactamase production status of Staph species were studied so as to know how best to provide effective intervention during outbreaks.

 

12. Odoki M, Bazira J, Moazam ML and Agwu E                               

Health-point survey of bacteria urinary tract infections among suspected diabetic patients attending clinics in Bushenyi district of Uganda (SBPJ) 2015; 1 (1): 5 –9.          

See  http://www.spparenet.us/SBPJ/?page_id=147

 

Key Message: In this paper bacterial agents of urinary tract infection were surveyed so as to assist diabetic patients in associated disease management.

 

13. Ihongbe JC, Moazzam ML, Pazos V and Agwu E   

Non-target oral bacterial resistance to Cotrimoxazole in   HIV/AIDS patients living in South Western Uganda. (SBPJ) 2015; 1 (1): 1 –4.  See the paper through the link below.  http://www.spparenet.us/SBPJ/?page_id=113               

 

Key Message: In this paper, cotrimoxazole commonly used as routine prophylaxis among HIV infected and AIDS patients were tested for their activity against non-target oral bacteria and we found that use of cotrimozole induced some resistance to oral bacteria bwith the ultimate goal of providing information on possible development of resistance which may negate the good report of cotrimoxazole in HIV/AIDS management.

 

14. Agwu E., Ihongbe JC, Ezeonwumelu JOC, Moazzam ML. Baseline burden and antimicrobial susceptibility of pathogenic bacteria recovered from oral lesions of HIV/AIDS patients in South-Western Uganda. Oral Science International, 2015; 12 (2): 59-66. DOI: 10.1016/S1348-8643(15)00018-.

 

Key message: In this paper, the oral load of potential pathogenic bacteria in HIV/AIDS were surveyed and their antibiotic susceptibility status outlined, so as to get an insight of reservoir pathogen base that could serve as a source of disease outbreak. This information is needed to provide effective intervention.

 

15.  Adiukwu PC, Kayanja FIB, Nambatya G, Adzu B, Twinomujuni S, Twikirize O, Ganiyu AA, Uwiduhaye E, Agwu E, Tanayen JK, Nuwagira P and Buzaare P. [2013] Anti-Inflammatory and Anti-Pyretic Activity of the Leaf, Root and Saponin Fraction from British Journal of Pharmacology and Toxicology. 4(2): 33-40,

 

Key message: In this paper, the validation of anti-inflammatory and anti-pyretic activity of local leaf and root extracts of Vernonia amygdalina significantly improved the overall management of pyretic and inflammatory diseases at the grass root and strongly discouraged the dependence of imported drugs for same illnesses.  This paper therefore has health policy, research, academic, clinical and public health implications. 

 

16. Tirwomwe JF, Agwu E, M. Samula, [2013]. The magnitude of tooth bud extraction in Uganda International journal of medicine and medical science. vol 5 (10), pp.450-455

 

Key message: In this paper, we showed that toothbud extraction in Uganda significantly and positively affects the epidemiology of oral disease among local inhabitants of resource limited settings like Uganda.    

 

17. Ezeonwumelu JOC, Omolo RG, Ajayi AM, Agwu E, Tanayen JK, Adiukwu CP, Oyewale AA, Adzu B, Okoruwa AG and Ogbonnia SO. 2012. Studies of Phytochemical screaning, acute toxicity, and anti-diarrhoea effect of aqueous extract of Kenyan Tithonia diversiflia leaves in rats. British Journal of Pharmacology and Toxicology. 3 (3): 127-134.

 

Key message: In this paper, the authentication of local aqueous extract of Kenyan Tithonia diversiflia leaves as having anti-diarrhoea effect and fit for human consumption improved the management of diarrhoea at the grass root and discouraged the overdependence of imported drugs for diarrhoea management in resource limited settings. This paper therefore has policy, research, academic, clinical and public health implications. 

 

18. Agwu E. [2011] Distribution of Community acquired typhoid fever among febrile patients attending clinics in Bushenyi, Uganda: case study of the year 2005. Journal of Medical Microbiology and Diagnosis. Vol 1, issue 101, pages 1-4, (doi:10.4172/2161-0703.1000101)

 

Key message: This paper confirmed that typhoid fever is highly prevalent among patients clinically diagnosed with febrile illness and deserves equal attention given to other agents of febrile illness if the patients’ health condition is to be ameliorated. This paper therefore has policy, research, academic, clinical and public health implications.

 

19. Agwu E, John C. Ihongbe, Brenda A. McManus, Gary P. Moran, David C. Coleman and Derek J. Sullivan. 2011 Distribution of yeast species associated with oro-pharyngeal candidiasis in HIV-infected patients in Southwest Uganda. Medical Mycology. Medical Mycology,1–5 , doi: 10.3109/13693786.2011.604862

 

Key message: This paper confirmed that the change of yeast population pre-dominating oral lesions of HIV/AIDS,   from Candida albicans to non-Candida albicans (known to inherently resist conventional antifungals), explained the persistent oral lesions observed among the studied population. This should guide the review of the treatment protocol in yeast research. This paper clearly improved our detailed knowledge of yeast population found in the oral lesions of HIV/AIDS patients receiving routine nystatine and cotrimoxazole per unit time, and has since its publication positively improved oral lesions management outcome. The result has policy, research, academic, clinical and public health implications.

 

20. E. Agwu, V. Pazos, J. C. Ihongbe & J. Ssengendo (2011): Appraisal of the inherent socio-demographic dynamics of HIV/AIDS epidemic in four districts of South-Western Uganda, SAHARA-J: Journal of Social Aspects of HIV/AIDS: An Open Access Journal, 8:3, 150-155

 

Key message: This manuscript confirmed that characteristic changing aspects of socio-demographic factors related to HIV/AIDS distribution was responsible for continued escalation of HIV/AIDS pandemic even when biomedical and clinical research recommendations are fully implemented in the studied population. The result has health policy, research, academic, clinical and public health implications 

 

21. Agwu E. The need for a Master of Sciences degree program in Microbiology in Uganda. African Journal of Health Professions Education, 2010, 2 (1): 21-22

 

Key message: This paper confirmed the need for M. Sc. degree programs in Microbiology despite the existence of clinically based M. Med programs, to help to improve on biomedical research, academic and capacity building. Now there are many Uganda East Africa Universities has started the program. Increased research capacity output by locally trained Microbiologists confirms the significance.

 

22. Agwu E, Ihongbe J.C. and Inyang N.J. Prevalence of Quinolone susceptible Pseudomonas aeruginosa and Staphylococcus aureus in delayed-healing diabetic foot ulcers in Ekpoma Nigeria. Wounds 2010; 4: 100-105.  http://www.ncbi.nlm.nih.gov/pubmed/25901956?dopt=Abstract

 

Key message: Delayed healing diabetic foot ulcers with microbial aetiology accelerates healing, when microbial aetiology is correctly identified and appropriate antibiotics administered. It is now clear that wound healing even in debilitating disease conditions is determined by underlying health conditions and appropriate diagnosis has significant impact on management and prognostic outcome. 

 

23. Agwu E, Ihongbe JC, Pazos V, Tirwomwe JF. Zero prevalence of parasites associated with oral lesions of HIV infected and AIDS patients in South Western Uganda. African Health Sciences 2009; 9(4): 239 – 244

 

Key message: This paper confirms that parasites are absent and may not be involved in causing oral lesions of HIV/AIDS among patients living in resource limited settings despite observed classical clinical signs and symptoms that could have suggested otherwise and implicated the parasites. Laboratory exclusion of parasites clinically implicated in oral disease is promising good news for oral lesion management in patients with debilitating disease conditions. The result has health policy, research, academic, clinical and public health implications 

 

24. Ojulong J, Mwambu T, Joloba M, Agwu E, Bwanga F, Najjuka C & Kaddu-Mulindwa D. Prevalence of Methicillin resistant Staphylococcus aureus (MRSA) among isolates from surgical site infections in Mulago hospital- Kampala, Uganda. The Internet Journal of Infectious Diseases 2009 Volume 7 Number 2

 

Key message: In this paper we showed that surgical sites were predominated by Methicillin resistant AIDS defining Staphylococcus aureus (MRSA) infection. This information impacted positively on surgical sites wound management in resource limited settings. The result has health policy, research, academic, clinical and public health implications.

 

 

25. Agwu E., Ihongbe J.C., Okogun G.R.A., Inyang, N.J. High incidence of co-infection with malaria and typhoid in febrile HIV Infected and AIDS patients in Ekpoma, Edo State, Nigeria. Brazilian Journal of Microbiol 2009; 40 (2):329-332

 

Key message: In this paper, we found that haemolytic anaemia in febrile HIV/AIDS disease was caused by malaria and typhoid and also confirmed the known fact that co-infection of Bacteria, parasite and virus explained the poor prognosis seen among studied population. Thus malaria and typhoid helped HIV disease fast progression to AIDS by deep tissue inflammation and subsequent increased leukocyte migration while reduction of leukocyte population at inflamed site assisted faster establishment of malaria and typhoid by Plasmodium and Salmonella species respectively. The result has health policy, research, academic, clinical and public health implications 

 .

26. Ihongbe J.C., Agwu E., Inyang N.J., Pneumococcal pneumonia complicates presentation of pulmonary Tb & pseudomembranous candidiasis, predictive of unknown HIV infection in Ekpoma Nigeria: Internet J Micro. 2008; 5 (2)

 

Key message: In this paper we showed the magnitude of co-infection between pneumonia and tuberculosis and we also outlined how pseudomembranous candidiasis can act as a predictor of unknown HIV infection status in resource limited settings. Understanding the fact that a major disease like pneumonia complicated Tb presentation by acting as under lying disease easily missed in routine diagnosis and use of certain oral lesions as predictor of unknown HIV disease status is promising and has positive prognostic value. The result has health policy, research, academic, clinical and public health implications 

 

27. Agwu E., Ihongbe J.C., Tirwomwe J.F., Pazos V. Tirwomwe M. and Casadesus L. Appraisal of Oral Lesions status of HIV/AIDS Patients in South Western Uganda. Brazilian Journal of Oral Sciences 2008; 7, (26): 1591-1595

 

Key message: In this paper, defining the magnitude of oral lesions by situational assessment of the oral lesions status of HIV/AIDS patients significantly impacted on the overall prognosis of the studied population. Apparent malnutrition among most of the participants who sparingly used their mouth for food impacted positively on the need for further research to restore the mouth to the patients. The result has health policy, research, academic, clinical and public health implications 

  

28. Agwu E, Ihongbe JC, Okogun GRA, Ezeonwumelu JOC, Igbinovia O. Chromobacterium violacium associated with recurrent vaginal discharge among apparently healthy females in Ekpoma Nigeria. OJHAS, 2007, 1: 2.

 

Key message: In this paper, the discovery of Chromobacterium violacium involvement in recurrent vaginal discharge different from the known agents significantly impacted on the treatment outcome and definitely had health policy, research, academic, clinical and public health implications 

 

29. Okpala, H. O., Agwu, E., Nwaopara A.O.,  Agba, M I. Evaluation of the Efficacy of Praziquantel on Urinary Scistosomiasis in Katanza Village, Akwanga, Nasarawa State, Nigeria. J Integrative Med & Biomed Research 2006 1 (1): 35-38

 

Key message: In this paper we confirmed that community based massive drug administration based on previous laboratory based investigation remains a powerful intervention approach in the control of tropical infections and that praziquantel remain useful in control of urinary schistosomiasis in disease endemic and resource limited settings. This result has health policy, research, academic, clinical and public health implications 

 

30. Agwu E, Ohihion A A, Agba M I, Okogun G R A, Okodua M, Tatfeng YM, Nwobu G.O. Incidence of Streptococcus pneumoniae Infections Among Patients Attending Tuberculosis Clinics in Ekpoma, Nigeria. SEMJ, 2006, 7, (1)

 

Key message: In this paper: we show that tuberculosis patients are frequently co-infected with pneumonia which may go undetected in in routine clinical practice thereby posing a public health, health policy, research, diagnostic, academic and clinical implications. 

 

 

31. Agwu, E., Agba, M.I., Esumeh, F.I., Tatfeng, Y.M., Ongey, J.Y., Uzoaru, S.C., Okodua, M., Turray A.A. Susceptibility status of Streptococcus pneumoniae against streptomycin and rifampicin commonly used for pulmonary tuberculosis. Journal of Applied and Basic Sciences, 2005, 3 (1&2): 33-36.  

 

Key message: In this paper, we confirmed that when lethal dose are applied during Tb treatment, Streptomycin can act as broad spectrum antibiotics which also effectively clears the underlying agents of pneumonia. However the consequence of exposing Streptococcus pneumoniae to sub-lethal dose of streptomycin can be catastrophic leading to multidrug resistant agent and Tb and Pneumonia treatment failures. This result has health policy, research, academic, clinical and public health implications 

 

32. Agwu E, Ohihion AA, Ogbimi AO, Ongey JY, Agba MI, Igbinovia O. Heterophile antibodies among normal University of Benin students Nigeria Shiraz Electronic Medical Journal, 2005, 6, ( 3 & 4).

 

Key message: In this paper, we outlined the predictive value of heterophile antibodies in the diagnosis of Ebstein-bar virus in apparently health population.

 

33.  Agwu E., Agba M.I Nwobu G.O. Ongey J.Y. Inyang N.J. Imharebhor J.A. Antimicrobial resistant profile of Streptococcus pneumoniae isolated from suspected tuberculosis patients in Ekpoma and its environs: SEMJ, 2004, 5, (3).

 

Key message: In this paper, we outlined the pattern of resistance of Streptococcus pneumoniae to conventional antibiotics. This has already positively impacted on the incidences of treatment failures in studied population.  

 

34. Okpala, H. O., Agwu, E., Agba, M. I., Chimezie, O. R., Nwobu, G. O., Ohihoin, A.A. A survey of the prevalence of schistosomiasis among pupils in Apata and Laranto Areas in Jos, Plateau State, Nigeria. OJHAS, 2004, 3, (1).

 

Key message: This paper outlines the endemicity of schistosomiasis in the Nothern Nigeria towns of Apata and Laranto. This result had health policy, research, academic, clinical and public health implications. 

 

35. Okogun G.R.A., Agwu E., Imomon S. M, Okam A. Sero-prevalence of HIV, and AIDS associated opportunistic infections in some parts of Northern Nigeria. Emirates Medical Journal, 2005, 23(1), 35-39.

 

Key message: Mapping the opportunistic infections of HIV was needed to guide HIV care givers on the regional distribution of opportunistic infections. This result has health policy, research, academic, clinical and public health implications 

 

36. Tatfeng Y.M., Nwobu, G.O., Okokua, M.A., Okogun, G.R.A., Agba, M.I. Agwu, E. Effect of Lamivudine (Epivir), Nevirapine (Vivumine) and Stavudine (Stavir), on CD4+ Count of HIV patients attending University of Benin Teaching Hospital, Benin Edo State, Nigeria . Kuwait Medical Journal, 2005, 37 (2): 86-90.

 

Key message: In this paper, the effect of Lamivudine (Epivir), Nevirapine (Vivumine) and Stavudine (Stavir), on CD4+ was reported and understanding the effect of HAART on CD4 cell count is needed for effective monitory and evaluation and for prediction of HIV disease progression.

 

37. Agwu E, Isibor J.O., Okogun G.R.A., Agba M.I. Ekpoke J., Onyebuagu P.C., Nwaopara A.O. Evaluation of the immunogenicity of locally prepared somatic antigens of Salmonella typhi. Nig J Biomed Engin, 2003, (2):14 -18.  

 

Key message: Locally prepared antigens are highly immunogenic and therefore can act as suitable alternative for imported diagnostic tools. This result had health policy, research, academic, clinical and public health implications 

 

38. Agwu, E., Agba, M.I., Nwobu, G.O., Isibor, J.O., Okpala, H.I., Ohihion, A.A., and Uzoaru, S.C. Pattern of UTI Among Female Students of National Veterinary Research Institute Vom. J Biomed Sc in Africa 2004, .2, (2):15-17.

 

Key message: In this paper, we showed that apparently health females harboured urinary tract infection obtained from poor hygiene and from frequent genital manipulation. This result has health policy, research, academic, clinical and public health implications 

 

39.  Okodua M.A., Nwobu G.O., Tatfeng Y.M., Ongey J.Y.,  Agwu E. Incidence of HIV-related pulmonary tuberculosis in Edo State Nigeria. SEMJ, 2004, 5, (1)

Key message: In this paper we reported the magnitude of HIV and tuberculosis co-infection and recommended effective management protocols. This result is useful to health policy makers, researchers, academicians, clinicians and health sector disease epidemiologists

 

40 Isibor J.O., Ogbomoiko D.O., Nwobu G.O., Agwu E., Okogun G. R. A., and Anyanlere M. Serological Survey of patients clinically diagnosed for Enteric Fever in Benin City Edo State Nigeria. J App and Basic Sc, 2003, 1, (1&2) 13-16.

 

Key message: In this paper, we confirmed the usefulness of laboratory investigations in the diagnosis and management of enteric fever and for effective intervention in enteric fever management full knowledge of disease aetiology is very helpful

 

41. Okpala H. O., Agwu E. Adamu A. U., Agba M.I. Nwobu G. O., and Idiong D. U.  Observations on the prevalence of malaria parasites in women attending ante-natal clinic in Jos University Teaching Hospital. International Journal of Environmental Health and Human Development, 2003. 4 (1): 55-57.

 

Key message: In this paper we showed that malaria has server and unpredictable health consequence determined by the trimester of the pregnancy and underlying medical conditions. This result is useful to health policy makers, researchers, academicians, clinicians and health sector disease epidemiologists

 

42. Uzoaru SC, Agwu E, Abdulahi J, Ureme SO, Turay AA, Digbang K, Proph TP, Nwaopara A. Bioterrorism and Microbes in Biological Warfare in practice. Nigerian Journal of Biomedical Science in Africa, 2004, 3 (1): 54-58.

 

Key message: In this paper we reviewed the trend and magnitude of bioterrorism in biological warfare and therefore increased the reader’s alertness on the subject matter. This result is useful to health policy makers, researchers, academicians, clinicians and health sector disease epidemiologists among others

 

43.  Uzoaru SC, Ureme SO, Nwobu GO, Duru LAD, Akhatise EAK, Asimota JO, Agwu E, Agba MI, Anyanwu R. Antioxidant Tocopherol concentration and some hematological parameters on HIV/AIDS patients in Nigeria. Journal of Biomedical Science in Africa 2004, 2 (1): 8-11.

 

Key message: In this paper, we showed that effective use of antioxidant and tocopherol impacted positively on the prognostic status of HIV patients and significant derail the progression of HIV infection to AIDS 

 

44. Uzoaru S.C., Agbonlahor, D.E Aloamaka, C.P., Turay, A.A., Aigbiremolen, A., Proph T.P., Onyebuagu, P.C., Erhabor T., Igwe C.U., Agwu E.. Effects of Triphasic Exercise on Blood Rheology and Pathophysiology. JMLS 2005, 14 (2): 13-22

 

Key message: This paper confirms the usefulness of exercise in keeping fit and it has overall good impact response to treatment because any form of exercise during infection treatment encourages the microorganisms to remain in circulation thereby increasing the chance of coming into contact with the lethal plasma dose that will effect cure. 

 

 

B. Three textbooks published

45.  Agwu E, (2014). Human Microbial Infections, 1st edition, Spparenet Ltd, Uganda, pg 1-666

 

46. Agwu E. (2014). Research Methods in Biomedical Sciences, 2nd Edition, Spparenet Ltd, Uganda, pgs 1-200

 

47. Agwu E, (2010). Laboratory Mannual in Practical Microbiology and Parasitology. 2nd Edition, Spparenet Ltd, Uganda, Pgs 1-170. 

 

c. Three book chapters published AFTER last promotion in January 1, 2011,

 

48. Dafewhare EO, Agwu E, Ezeonwumelu JOC, Shaban A. (2013). A Review of Clinical Manifestations of Gangrene in Western Uganda in: Gangrene Management - New Advancements and Current Trends; Intech publishers, http://dx.doi.org/10.5772/55862

 

Key message: This paper outlined the magnitude of superficial gangrene and contains surrogate diagnostic data which has now broadened the index of clinical suspicion in the regional diagnosis of gangrene. This paper significantly impacted on the capacity of healthcare providers to detect, manage, prevent and control gangrene in resource limited settings.   

 

49. Ekanem PE, Ajaye MA, Ekanem M, Agwu E, (2013). Impact assessment of Diabetes on gangrene in South Western Uganda I: Gangrene Management - New Advancements and Current Trends; Intech publishers, http://dx.doi.org/10.5772/56107

 

Key message: In this paper, we showed how: diabetes determined the spread of gangrene and how poor diabetic service uptake, poor information storage and retrieval, poor health facilities, poor socio-economy, demography and cultural background of participants significantly impacted on the epidemiology of diabetic gangrene in this region. This paper therefore has policy, research, academic, clinical and public health implications.

 

50. Agwu E, Dafiewhare OE and Ekanem PE (2011). Possible Diabetic-Foot Complications in Sub-Saharan Africa, Global Perspective on Diabetic Foot Ulcerations, Thanh Dinh (Ed.), ISBN: 978-953-307-727-7, InTech, Fom http://www.intechopen.com/articles/show/ 

 

Key message: In this study, peripheral nephropathy, vaginal Candidiasis, urinary tract infection, skin Infection and obesity among others frequently complicated diabetic foot and limited diabetic serves clinics worsened by poor up-take of few available ones by the community made it difficult to confirm the true picture of diabetic foot in the studied population and area. It became clear after this publication that absence of specialized diabetic clinics and limited resources may have negatively impacted on our current knowledge of the disease epidemic in the locality.  

 

 

B. Published Abstracts

 

51. Agwu E, Ihongbe JC, Inyang NJ. Gentian violet can be used as topical oral anti-fungi and anti-stigma agent by people living with HIV/AIDS" via Treatment strategies and economic aspects in invasive fungal infections P 859" Poster , 31st March 2012 at the European Congress of Clinical Microbiology and Infectious Diseases [ECCMID]. London.

 

Key message: This abstract confirmed that Gentian violet can be diluted to get a concentration which remains effective antifungal agent but will not stain the mouth to avoid HIV/AIDS associated stigma.

 

52. Agwu E, Guarimpa M, Gulemye I, Abuse of antimalarial drugs in treatment of febrile patients clinically diagnosed of malaria in Bushenyi District Uganda" via Highlights of parasitic Disease research 0 340" oral. 31st March and 1st April 2012 at the European Congress of Clinical Microbiology and Infectious Diseases [ECCMID], London.

 

Key message: This abstract highlights the need healthcare providers to confirm malaria dip stick test result with conventional malaria microscopy before commencing malaria treatment to avoid antimalarial abuse. The full data will be published in relevant peer reviewed journals.

 

53. Agwu E., Ihongbe JC, Pazos V. Regional mapping of oropharyngeal carriage of yeast species associated with oral lesions of HIV/AIDS patients in South Western Uganda via infectious, re-emerging diseases PO1038_22 oral, September 22, 2011, at the 7th Annual Scientific conference MAK-CHS and 19th UNACOH annual scientific conference, Speke Resort Munyonyo Kampala, Uganda.

 

Key message: This abstract outlines the great difference in population structure of oropharyngeal yeast existing between four districts located in South Western and South southern Uganda. This full details was later published in Medical Mycology.

 

54. Agwu E. Distribution of community acquired typhoid fever among febrile patients attending clinics in Bushenyi, Uganda a case study of year 2005 PS1036_22 oral, September 37, 2011, at the 7th Annual Scientific conference MAK-CHS and 19th UNACOH annual scientific conference, Speke Resort Munyonyo Kampala, Uganda.

 

Key message: This abstract showed the relevance of typhoid in management of febrile illness. The full data was later published in Journal of Medical Microbiology and Diagnosis.

 

55. Agwu E and Joram GO. Pattern of malaria prevalence among febrile patients treated with chloroqine, fansider, and quinine in South Western Uganda. PS1037_22 oral, September 22, 2011, at the 7th Annual Scientific conference MAK-CHS and 19th UNACOH annual scientific conference, Speke Resort Munyonyo Kampala, Uganda.

 

Key message: This abstract highlights the resistance of malaria parasites to conventional antimalarial and confirmed the reason for shifting the first line malaria treatment from chloroquine to atemisine based combination. The full data will be published in relevant peer reviewed journals.

 

56. Agwu E, Ekanem P, and Magithi MI. Sentinel survey of the prevalence of syphilis infection among patients clinics in Bushenyi district Uganda. PS1038_22 Poster, September 22, 2011, at the 7th Annual Scientific conference MAK-CHS and 19th UNACOH annual scientific conference, Speke Resort Munyonyo Kampala, Uganda.

 

Key message: This abstract depicts a sero-survey of syphilis among patients attending clinics in Bushenyi. The full data will be published in relevant peer reviewed journals. 

 

57. Alkali B, Isa IA, Agwu E, Fada FS: Antimicrobial activities of the ethanoloic extract of Gardenia erubescens on some clinical pathogenic bacterial isolates. Nine Annual conference of the Association of Medical Laboratory Scientists of Nigeria held at Royal Tropicana Hotel Kano state Nigeria from 21-25th November 2011.

 

Key message: This abstract confirmed that Gardenia erubescens has antimicrobial activity on some clinical pathogenic bacterial isolates and therefore can be used as surface agent. The full data will be published in relevant peer reviewed journals

 

58. Alkali B, Isa IA, Agwu E, Fada FS: Research on toxicity level [LD50] and aphrodisiac activity of Gardenia erubescens in male albino rats. Nine Annual conference of the Association of Medical Laboratory Scientists of Nigeria held at Royal Tropicana Hotel Kano state Nigeria from 21-25th November 2011.

 

Key message: This abstract confirmed that Gardenia erubescens has aphrodisiac activity on some clinical pathogenic bacterial isolates and therefore can be used as surface agent. The full data will be published in relevant peer reviewed journals

 

59. Agwu E, L. Wambua, L. Titus. Sentinel survey of typhoid prevalence among febrile patients attending clinics in Bushenyi district of Uganda; Abstract No: 965. 19th ECCMID, Helsinki, 2009.

 

Key message: In this abstract we reported the magnitude of Typhoid in febrile illness and information needed by researchers, academicians, clinicians and health sector disease epidemiologists among others

 

60. Agwu E, G. Tananyen: Randomized health-point surveillance of human gastro-intestinal parasites among patients attending a teaching hospital in Ishaka, Uganda; Abstract No: 125119th ECCMID, Helsinki, 2009

 

Key message: This abstract outlined the prevalence of intestinal parasites among hospital attendees in Bushenyi district. This result is useful to researchers, academicians, clinicians and health sector disease epidemiologists among others

 

61. Agwu E, J. Ihongbe, N. Inyang, Prevalence of quinolone susceptible Pseudomonas aeruginosa and Staphylococcus aureus in delayed-healing diabetic foot ulcers in Ekpoma, Nigeria; Abstract No: 1395, 19th ECCMID, Helsinki, 2009

 

Key message: This abstract showed the impact of microorganism in delayed wound healing. This result is useful to health policy makers, researchers, academicians, clinicians and health sector disease epidemiologists among others. It has since been published in wounds journal see no 18

 

62. Agwu E., Ihongbe JC, Pazos V. High co-trimoxazole resistance by bacteria associated with oral lesions in a population of Ugandan HIV infected and AIDS patients. Abstract number: R2292, 18th ECCMID, Barcelona, Spain, 2008.

 

Key message: This paper outline how oral bacteria developed resistance to cotrimoxazole used in routine prophylaxis in HIV/AIDS disease management

 

23.   Service to national and or international bodies

 

  1. United Nation Global Compact via Spparenet Ltd
  2. Youth Corps Member (NYSC)
  3. External Examiner to Makerere College of Veterinary Medicine

 

24.Extra-curricular activities

Reading, Writing, Teaching, Innovative thinking, Taking up Positive challenges and praying. 

 

25.Any physical challenge?

None

 

26.   Names and addresses of three (3) referees  

 

1. Ihongbe J.C., PhD. Professor of Microbiology, Department of Medical Laboratory Sciences, Babcock University, Illisan Remo, Ogun State, Nigeria. ihongbej@yahoo.com ; Phone: +2348072319857.

 

2. Dr. Moazzam Lodhi. Senior Lecturer Department of Public Health, Kampala International University, Western Campus, Box 71, Ishaka Bushenyi Uganda,

Tel: +256792067022  E-mail: moazzamlodhi@hotmail.com

 

3. Tatfeng YM, PhD. Professor of Immunology, Department of Medical Laboratory, Sciences, Niger Delta University, Wilberforce Island, Bayelsa State, Nigeria. E-mail: youtchou@yahoo.com  ; Tel: 2348037454909

 

4. Dr. Tita-Nwa, Freddy, PhD. National Institute of Health, NIA, Lab. of Cellular and Molecular Biology, Baltimore, Maryland, USA. Tel: +1-410-588-8467; Fax: +1-410-588-8026. E-mail: titanwafd@mail.nih.gov